What Is Osteoarthritis?
Osteoarthritis (OA) causes joint cartilage to become stiff and lose elasticity, making it more susceptible to damage and to deterioration. The tendons and ligaments then stretch, which causes pain. As the condition worsens, bones can start to rub against each other.
Osteoarthritis Clinical Trials
3A Research has a strong track record conducting clinical trials for osteoarthritis. We are seeking individuals to participate in pain clinical studies. Compensation will be given for time and travel.
Qualifications we typically require for our osteoarthritis clinical research programs:
- Healthy male or nonpregnant female aged 35 years or older with a clinical diagnosis of OA of the knee with the following criteria:
- Symptoms for at least 6 months prior to screening, AND
- Knee (not referred) pain for 15 days of the preceding month (knee pain due
to OA and not due to other conditions such as bursitis, tendonitis, etc.), AND
- The pain in the target knee required the use of NSAIDs or acetaminophen (topical or oral treatments).
- Had an X-ray of the target knee, taken no more than 1 year before baseline, showing evidence of OA
- After discontinuing all pain medications for at least 7 days, had at least moderate pain on movement for target knee
- Able to tolerate rescue medication with acetaminophen.